Abstract: This work investigates computationally the modeling of sugarcane bagasse pyrolysis in a bubbling fluidized bed reactor. An Euler–Euler multiphase approach, as invoked by the open code MFIX (Multiphase Flow with Interphase eXchanges), is adopted, and the simulations are carried out in a two-dimensional Cartesian domain. While several pyrolysis kinetic models have been developed for wood, coal, and generic biomass, generally using thermogravimetric analysis, no such model has been specifically tested or adapted to simulate sugarcane bagasse pyrolysis in fluidized bed reactors through computational fluid dynamics. In the present study, seven pyrolysis kinetic models available in the literature are implemented as MFIX user-supplied routines and evaluated within given operational temperature ranges. Initially, well-established wood pyrolysis results are used to validate the implementations. Following validation, six kinetic schemes are employed to simulate sugarcane bagasse pyrolysis. Results for the products distribution, formation reaction rate profiles, and tar composition at different operating temperatures of the fluidized bed reactor are obtained for all models and compared to published experimental results. Based on the assessed predictive performances of the models, indications are drawn for the most appropriate models to simulate the reactor under different operating conditions.